Tobias Weimer
Product Specialist LC-MS
Tobias Weimer studied chemistry at the Philipps University in Marburg. His passion for analytical chemistry and chromatography was already awakened in high school and deepened during his studies with a specific focus on analytical separation techniques. His path led him from liquid chromatography in the field of LC columns to LC and LC-MS systems. He has been in contact with users for several years and talks about workflows and solutions.
DAY 1: February 27th, 2025
SESSION: Extractable Leachable Analysis of Commercially Available Catheters
◆ Extraction conditions (solvents, pH, duration) significantly impact the E&L compounds detected.
◆ Major extractables identified included plasticizers, amines, and long-chain amides, varying among catheter types.
◆ The Revident LC/Q-TOF system proved effective for both targeted and untargeted analysis of E&L compounds.
◆ Advanced data analysis techniques were crucial for compound identification in complex E&L profiles.
◆ In-source fragmentation and coelution of compounds presented challenges, requiring both hardware and software solutions for accurate analysis.
DAY 2: March 8th, 2024
SESSION: Perfecting Extractable and Leachable Testing – Explore multiple analytical approaches to accurately identify and quantify extractable and leachable compounds
◆ Agilent comprehensive portfolio to mitigate risk of E&L.
◆ Analytical Workflow strategies & Solution:
- Scouting approach using modern molecular spectroscopy solution.
- Identification & quantitation of E&L for volatile/ Semi-volatile Impurities using GCMS solution.
- Streamlining Elemental Impurities, Extractables and Leachable Workflows Flow with Agilent Time Trap Analytical Solution.
